Powering the Cell: Mitochondria


Together Harvard University and XVIVO developed this 3D animation journey for Harvard's undergraduate Molecular and Cellular Biology students about the microscopic world of mitochondria. The animation highlights the creation of Adenosine Triphosphate (ATP) -- mobile molecules which store chemical energy derived from the breakdown of carbon-based food. ATP molecules act as a kind of currency, imparting chemical energy to power all the functional components of cellular activity. This piece is the second in a series of award winning animations XVIVO is creating for Harvard's educational website BioVisions at Harvard. The first program, Inner Life of the Cell, received international acclaim and can be seen both on our website and the BioVisions site.


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Mitochondria - Mitochondrian


Free Science Help at Brightstorm! brightstorm.com The structure of mitochondrian.


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mitochondria ATP synthesis


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TEDxIowaCity - Dr. Terry Wahls - Minding Your Mitochondria


Dr. Terry Wahls learned how to properly fuel her body. Using the lessons she learned at the subcellular level, she used diet to cure her MS and get out of her wheelchair.


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Learn Biology: Cells—Mitochondria


LIMITED TIME ONLY! Jasmine V App $1.99 mhlo.co Mahalo biology expert Mary Poffenroth tells you about the mitochondria in our cells. Mitochondria --------------------------------------------------------------------- Mitochondria are the powerhouses of the cell, generating most of the cell's energy supply. Within the cell's mitochondria, the food we eat gets turned into energy that we use. That energy is ATP, or adenosine triphosphate, which transports chemical energy within cells. Mitochondria are found in almost all eukaryotic cells.c Under the Microscope --------------------------------------------------------------------- Mitochondria have an outer membrane and an inner membrane with many inner foldings called crystae. Mitochondria also assist with cell growth, cell cycle and cellular death. They even have their own DNA, which is evolutionary evidence that mitochondria and chloroplast were once prokaryotic organisms in the distant past.c Read more by visiting our page at: www.mahalo.com


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The Way Energy is Made - Mighty Mitochondria in Action!


Where does mitochondrial disease come from? How does your body make energy? Why are the mitochondria important for life, diseases, and aging? Learn all about it in this 3D animation designed by students from the Center for Digital Imaging Arts at Boston University in cooperation with MitoAction.org. MitoAction is dedicated to outreach and support that helps people with mitochondrial disease NOW. Learn all about Mito at mitoaction.org


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Cellular Respiration Occurs in Mitochondria | Cell Biology


Segment from the program Glycolysis and Cellular Respiration: The Biology of Energy. To purchase this program please visit www.greatpacificmedia.com


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Genotoxic Stress Meets Mitochondria: Integrating Aging Mechanisms


Air date: Wednesday, September 14, 2011, 3:00:00 PM Timedisplayed is Eastern Time, Washington DC Local Category: Wednesday Afternoon Lectures Description: The study of human genetic disorders and mutant mouse models has provided evidence that genome maintenance mechanisms, DNA damage signaling and metabolic regulation cooperate to drive the ageing process. In particular, age-associated telomere damage, diminution of telomere 'capping' function and associated p53 activation have emerged as prime instigators of a functional decline of tissue stem cells and of mitochondrial dysfunction that adversely affect renewal and bioenergetic support in diverse tissues. Constructing a model of how telomeres, stem cells and mitochondria interact with key molecules governing genome integrity, 'stemness' and metabolism provides a framework for how diverse factors contribute to ageing and age-related disorders. Exploiting the experimental merits of the mouse, we have shown that telomere dysfunction activates p53-mediated cellular growth arrest, senescence and apoptosis to drive progressive atrophy and functional decline in high-turnover tissues. The broader adverse impact of telomere dysfunction across many tissues including more quiescent systems prompted transcriptomic network analyses to identify common mechanisms operative in haematopoietic stem cells, heart and liver. These unbiased studies revealed profound repression of PGC-1α and PGC-1β and the downstream network in mice null for <b>...</b>


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Genetics of Autism From Chromosomes to Mitochondria.flv


This presentation is on the latest biomedical advances in understanding autism and elucidating its causes. This is important not just for a diagnosis, but for management, prognosis and counseling. Presenters: Dmitriy M. Niyazov, MD Section Head - Medical Genetics, Department of Pediatrics Ochsner Clinic Foundation Dr.Niyazov graduated from the University of Rochester School of Medicine and completed his residency in medical genetics at Emory University. He joined Ochsner Clinic Foundation in 2008. He works extensively with autistic children and has given several lectures to parents and providers on genetics of autism throughout Louisiana and Mississippi. Susan Fielkow, MD Section Head - Developmental Pediatics, Department of Pediatrics Ochsner Clinic Foundation Dr. Fielkow graduated from the University of Florida College of Medicine and completed her pediatric residency at Rush-Presbyterian in Chicago. She is board certified in general and developmental pediatrics and joined Ochsner for Children Child Development Center in 2001. Her professional interests include autism, ADHD, learning disabilities and behavioral problems.


Genetics of Autism From Chromosomes to Mitochondria The Society

PINK1/Parkin Derails Damaged Mitochondria


Thomas Schwarz shows how Parkinson's disease proteins quarantine damaged mitochondria by disconnecting them from the microtubule network.


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SENS5 - MitoSENS: Allotopic expression of mitochondrial genes - Part 1


© SENS Foundation 2011 - www.sens.org The Fifth SENS conference - Matthew O'Connor SENS Foundation Research Center Authors MS O'Connor, G. Swaminathan, S. Fazal, T. Jones, ADNJ de Grey The mitochondrion contains its own genome and encodes 13 proteins that are essential for the respiratory chain to function properly. Congenital mutations in many of the mitochondrial genes are the cause of serious disease phenotypes including diabetes, blindness, dementia, ataxia, epilepsy, and many other neurological disorders. Somatic mutations also accumulate in the mitochondria with normal aging. Allotopic expression of mitochondrial genes in the cell's nucleus is one approach to rescuing mitochondrial mutations. In our strategy, we utilize 5' and 3' elements to target mRNA to the outside surface of the mitochondria; this approach is a refinement of simple allotopic expression and is hypothesized to result in the co-translational import of the encoded proteins into the mitochondria. This approach is hypothesized to overcome obstacles (such as clogging of the mitochondrial import machinery by hydrophobic proteins) that many groups have experienced. Thus far, we have stably transfected 5 of the 13 mitochondrial genes into the nuclear genome of human cell lines and are characterizing the expression and function of these exogenously expressed genes. We will discuss current progress and future plans for replacing and/or making redundant the entire mitochondrial genome. We will also discuss <b>...</b>


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Mitochondrial DNA


genetree.com This animated tutorial is the third in a series of five videos exploring molecular genealogy. In this video you will discover how mitochondrial DNA can be a rich source of information for deep ancestry, going back thousands of years.


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BSCI 330 Extra Credit Mitochondria "POWER" Music Video


(LYRICS BELOW) That Cell Cray... Group: Elies Moumena, Shannon Morrow, Arjun Ivatury, Brook Teferi Professor Ades, BSCI330 Extra Credit. Music Video Im living in that cytoplasmic region, doing something mean to it Do it better than any organelle you've ever seen do it Scream from the haters, got a nice ring to it I guess every organelle needs his theme music No one cell should have all that power The clocks tickin I just count the hours Stop tripping Im tripping off the power No one cell should have all that power When I make atp, yall do the power clap, clap, clap, clap Cellular respiration yall know where its at Contain my own dna, who you know that does that that that that Floating in the cytoplasm, where is everybody at at at at at No one cell should have all that power The clocks tickin I just count the hours Stop tripping Im tripping off the power No one cell should have all that power In the cell world, I am the one chosen So I work all night that atp storing Ha, that atp storing This is way too much, I need a moment No one cell should have all that power The clocks tickin I just count the hours Stop tripping Im tripping off the power No one cell should have all that power Cellular Respiration, I'm Surviving I was in the membrane now I'm rhyming Where the ATP at HUH? Where you hiding?? I got that power make your cell so exciting It was a beautiful death, im going to the lysosoooome Letting everything go, letting everything go It was a beautiful death, im going to <b>...</b>


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Mitochondria The Site Of Respiration


Check us out at www.tutorvista.com In Journey into the Cell, we looked at the structure of the two major types of cells: prokaryotic and eukaryotic cells. Now we turn our attention to the "power houses" of a eukaryotic cell, the mitochondria. Mitochondria are the cell's power producers. They convert energy into forms that are usable by the cell. Located in the cytoplasm, they are the sites of cellular respiration which ultimately generates fuel for the cell's activities. Mitochondria are also involved in other cell processes such as cell division and growth, as well as cell death. Mitochondria: Distinguishing Characteristics Mitochondria are bounded by a double membrane. Each of these membranes is a phospholipid bilayer with embedded proteins. The outermost membrane is smooth while the inner membrane has many folds. These folds are called cristae. The folds enhance the "productivity" of cellular respiration by increasing the available surface area. The double membranes divide the mitochondrion into two distinct parts: the intermembrane space and the mitochondrial matrix. The intermembrane space is the narrow part between the two membranes while the mitochondrial matrix is the part enclosed by the innermost membrane. Several of the steps in cellular respiration occur in the matrix due to its high concentration of enzymes. Mitochondria are semi-autonomous in that they are only partially dependent on the cell to replicate and grow. They have their own DNA, ribosomes and can <b>...</b>


Mitochondria The Site Of Respiration Tutor Vista

Mitochondria: The Achilles Heel of Cancer Cells by Len Saputo, MD


Cancer cell mitochondria are the powerhouse and Achilles heel of tumor growth and metastasis. Cancer cells consume more than 5 times the energy than normal cells. This is contradictory to Otto Warberg's Nobel Prize winning thesis that cancer cells produced only limited amounts of ATP by burning glucose (glycolysis). Apparently, Warberg was measuring the combined energy production of both cancer cells and their surrounding stromal cells. Warberg believed that cancer cells derived their energy from sugar, but it turns out that it is the mitochondria that is making ATP. This effect may also explain why cancer patients lose weight as they get closer to dying. There are drugs such as Metformin and methyl jasmonate that can preferentially destroy mitochondria from cancer cells and leave normal mitochondria alone.


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Hypothyroidism reduces mitochondria; involved in congestive heart failure, Alzheimers, Mark Starr MD


fatnews.com Hi, this is Larry Hobbs @ FatNews.com. Hypothyroidism reduces the number and activity of mitochondria, the energy-producing cells, notes Mark Starr, MD, author of the wonderful book Hypothyroidism Type 2: The Epidemic. Mitochondria make up one-third of the weight of the heart muscle, Dr. Starr notes in this short audio clip from a speech he gave in 2007 at an Orthomolecular Conference. This appears to the connection as to how hypothyroidism can cause some forms of congestive heart failure where the heart muscle is too weak to pump enough blood to the rest of the body (cardiomyopathy). It's an energy problem. Dr. Starr's book contains the wonderful "Before" and "After" pictures showing X-rays of enlarge hearts that shrink back to normal size after the patient is given natural desiccated thyroid. A decrease in mitochondria also appears to be the connection of hypothyroidism to Alzheimer's, which Dr. Starr noted in another audio clip. Again, it's an energy problem. Why Not Try Desiccated Thyroid First? Why not try natural desiccated thyroid first for all of these conditions? Why not give natural desiccated thyroid a try for all of these conditions? It seems like a low-risk idea—a large potential benefit by doing this, with very little risk. If it were me, I would try natural desiccated thyroid for all of these conditions before trying anything else: Alzheimer's Disease Fertility Problem Menstrual Problems Congestive Heart Failure Depression Fatigue / Chronic <b>...</b>


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Mitochondria and oxidative phosphorylation


In this video I explain the role of the mitochondria in the process of oxidative phosphorylation. I also talk about some of the basic features of the mitochondria.


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AP Bio Project : Mitochondria, Chloroplasts, and Peroxisomes


Project for AP Bio. Rap starts around 5:40


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Lizzy's Walk for KSS - Mitochondrial Foundation Charity Event - Recap of June 25, 2011


LizzyPiroFoundation.info This video is a recap of the 1st Annual Lizzy Piro Foundation event held on June 25, 2011 To learn about KSS (Kearns Sayre Syndrome) - Mitochondrial Disease - Go to http [United Mitochondrial Disease Foundation (UMDF) website]. But first read the information below: "What is Mitochondrial Disease" ---------------------------------------- The Lizzy Piro Foundation was created by Lizzy's cousin, Keelin Walsh. Keelin & her siblings were each blessed with a monetary Christmas Gift (2010) to give to the charity of of their choice. Keelin decided to create this charity in honor of her cousin, Lizzy Piro, to support the research of the disease Lizzy has been battling since she was 4 yrs old. (LIzzy is now 12). The PIro Family, Keelin Walsh & all their supportive family & friends who helped kick off the Lizzy Piro Foundation encourage you to go to her link LizzyPiroFoundation to make whatever donation you can. Every $1 helps! -------------------------------------------- What is Mitochondrial Disease? Mitochondrial diseases result from failures of the mitochondria, specialized compartments present in every cell of the body except red blood cells. Mitochondria are responsible for creating more than 90% of the energy needed by the body to sustain life and support growth. When they fail, less and less energy is generated within the cell. Cell injury and even cell death follow. If this process is repeated throughout the body, whole systems begin to fail, and <b>...</b>


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Mitochondrial Theory of Aging


Have a question for Dr. Greger about this video? Leave it in the comment section at nutritionfacts.org and he'll answer it! VIDEO DESCRIPTION: The role of the detoxifying enzyme superoxide dismutase in staving off aging, cancer, and dementia and what we can do to boost its activity.


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Protein Transport (Mitochondria)


NDSU Virtual Cell Animations Project animation 'Protein Transport (Mitochondrial)'. For more information please see vcell.ndsu.edu Once translated, proteins are dispersed throughout the cellular environment. This section covers the transport of a protein into a specific organelle--the mitochondria.


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Mitochondria: Powerhouses of the cell


This is a computer animation of mitochondria in a human cell - an example of the capabilities of Neal Moore Communications in 2D and 3D animation. Computer animation allows us to model virtually any kind of environment - from microscopic views of life sciences research to a building, a bridge, a commuter rail system, etc. Contact Neal Moore Communications today for a consultation - you'll find our pricing for 2D and 3D animation very affordable, and of the highest quality. We look forward to hearing from you.


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Mitochondrion


In cell biology, a mitochondrion (plural mitochondria) is a membrane-enclosed organelle found in most eukaryotic cells.[1] These organelles range from 0.5 to 10 micrometers (μm) in diameter. Mitochondria are sometimes described as "cellular power plants" because they generate most of the cell's supply of adenosine triphosphate (ATP), used as a source of chemical energy.[2] In addition to supplying cellular energy, mitochondria are involved in a range of other processes, such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth.[3] Mitochondria have been implicated in several human diseases, including mitochondrial disorders[4] and cardiac dysfunction,[5] and may play a role in the aging process. The word mitochondrion comes from the Greek μίτος or mitos, thread + χονδρίον or chondrion, granule. Several characteristics make mitochondria unique. The number of mitochondria in a cell varies widely by organism and tissue type. Many cells have only a single mitochondrion, whereas others can contain several thousand mitochondria.[6][7] The organelle is composed of compartments that carry out specialized functions. These compartments or regions include the outer membrane, the intermembrane space, the inner membrane, and the cristae and matrix. Mitochondrial proteins vary depending on the tissue and the species. In humans, 615 distinct types of proteins have been identified from cardiac mitochondria,[8] whereas in Murinae <b>...</b>


Mitochondrion zabaaz

Of Cell structures (Mitochondria & Endomembrane System) A H2 Biology Project


We were tasked to create a video in the sole aim of enlightening viewers about any two systems or structures in the cell. we chose to focus on the derivation of the mitochondria and the systematic and efficient endomembrane system. Enjoy the video and please do comment or/and like. :) Thank you and God bless :)


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Cell Powerhouse: The Mitochondria


FE West invited Doctors of Medicine to talk about health, wellness and healing and how scalar energy can help in these processes.


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MITOCHONDRIAL DNA ~ SHE BE ON THAT SCIENCE (c) [HD]


nuedutainment.webs.com Mitochondria provide the energy a cell needs to move, divide, produce secretory products, contract - in short, they are the power centers of the cell. They are about the size of bacteria but may have different shapes depending on the cell type. Mitochondria are membrane-bound organelles, and like the nucleus have a double membrane. The outer membrane is fairly smooth. But the inner membrane is highly convoluted, forming folds called cristae. The cristae greatly increase the inner membrane's surface area. It is on these cristae that food (sugar) is combined with oxygen to produce ATP - the primary energy source for the cell.


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Mitochondrial DNA


mitochondrial DNA


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Mitochondria Targeting of Acinetobacter Baumannii Outer Membrane Protein A


Mitochondria Targeting of Acinetobacter Baumannii Outer Membrane Protein A Brief introduction of A. baumanii and OmpA and 3D Illustration of the apoptosis progresses triggered by bacterial OmpA through mitochondria dysfunction. Research design and results provided by JE-CHUL LEE, MD, Ph.D Dept. Microbiology, School of medicine, Kyungpook National University, South Korea 3D illustration by HYUN-HO HWANG Ms. Used programs - 3D Maya, zbrush, combustion, adobe photoshop, premiere pro and after effects. Acknowledgement to Animatus 3D desigh school in Korea


Acinetobacter Baumannii Apoptosis ompa Mitochondrial dysfunction Permeability Transition Pore 3D Biomedical illustration 37979

Mitochondria - Organelle within a cell (LEGO+Plasticine)


The description of a mitochondria and what it does =)


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Mitochondrion - Trials


Band: Mitochondrion Song: Trials Album: Parasignosis Genre: Death/Black Metal Lyrical Themes: Apocalypse, Occult, Disease, Gnosis Origin: Canada www.metal-archives.com www.myspace.com


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Mitochondrial Disease


This is a montage type of video to educate and raise awareness of mitochondrial disease. Included are just some of the faces of those affected by mitochondrial disease. There are thousands more out there...all of them need our help! To learn more about how you can make a difference and be a part of finding a cure please visit the United Mitochondrial Disease Foundation at www.umdf.org NO COPYRIGHT INFRINGEMENT INTENDED.


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MITOCHONDRIA RAP


Have you heard of a more fascinating organelle? Unarguably the most important of a cell. The mitochondria, An energy producing monster. Buy one in the next 90 seconds while we got our 50% offer. It's the site of respiration in the cell. Maybe evolved from symbiosis between 2 eukaryote cells, But who can really tell? The quadruple threat. The outer membrane, inter membrane, inter membrane space and the matrix Can you handle that? The reason we need oxygen at all And you breathe everyday so why not buy 'em all? It's function is to create energy through aerobic respiration So much going on it's hard to keep your concentration. If you're a cell staying active then you'll need this Especially the muscle cells of Chuck Norris The mighty mitochondria produces ATP It's the powerhouse for cell activity Both plant and animal cells need it so its known internationally And provides the energy eukaryotic cells will need To move, divide, produce secretory products, and contract Just give us a call and we'll ship it to you like that! If the cell is the car, Then the mitochondria's the engine that can that take it anywhere, No matter how far! Did we mention they got a double-membrane? That's a double whammy so if you don't buy it then youre insane in the membrane The inner membrane, A structure that's very complex It's the base for ATP synthesis It forms folds we call the cristae, Sticking around to rise up the SA Surface area makes room for more oxygen, CO2, and water If someone asks <b>...</b>


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Mitochondrial Protein Import


This video shows how proteins in the cytosol are delivered into a mitochondrion. This video is from: Essential Cell Biology, 3rd Edition Alberts, Bray, Hopkin, Johnson, Lewis, Raff, Roberts, & Walter ISBN: 978-0-8153-4129-1


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more mitochondrial ATP


biology 120

Who Was Mitochondrial Eve?


This video explains the concepts of Mitochondrial Eve and Y-Nuclear Adam, what their relationship to evolution and human lineage is, and how creationists claims about them are just pathetically wrong. Update: More news on the controversy over whether Neanderthals were the same species as humans.


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Anti-aging 3D medical animation mitochondria for Ninapharm,produced by Virtual Point


3D medical animation clip produced by virtual point of biological process. The purpose of Ninapharm's researches is to offer an "Anti-Aging Protection" package based on antioxidants. The idea is to determine several diseases directly linked to antioxidants deficiencies and to offer a package which is only based on vegetal or fruit plant extracts and combines different actives that provides the right solution for a Anti-Ageing process. ADS is dissolved quickly in the stomach and absorbed through the small intestine. ADS is channeled through the blood to reach the body cells across the cell membrane, crosses the mitochondria double membrane and attacks the free radicals and reduces them. ADS activates the antioxidant enzyme SOD. Antioxidant efficacy at cellular level protection and re-generation of the mitochondria through an innovative amphiphilic compound ADS. 3D Video clip produced by Virtual Point Multimedia.


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Mitochondria/Oxidations


This course is part of a series taught by Kevin Ahern at Oregon State University on General Biochemistry. For more information about online courses go to ecampus.oregonstate.edu 1. An interesting transporter is the Na+/Ca++ exchange pump (not shown in a figure in class, but described). It uses movement of Na+ in to cells to be a driving force for pumping Ca++ out. Remember than Ca++ stimulates muscular contraction. If Ca+ is not pumped OUT, its concentration in muscle cells remains high, stimulating contraction. Digitoxigenin is a compound from foxglove that binds the Na+/K+ ATPase, preventing development of a Na+ gradient. As a consequence, digitoxigenin increases Ca++ concentration, since Ca++ pumping requires a Na+ gradient. Digitoxigenin is used as a heart stimulant. 2. Nerve cells use the gradient of Na+ and K+ built up by the Na+/K+ pump to transmit signals. In nerve transmission, special "gates" open and close to allow Na to diffuse into nerve cells and K to diffuse out of nerve cells. 3. The first step in nerve transmission involves opening of Na+ gates. These allow Na+ to diffuse into the cell, since Na+ concentration is higher outside of cells than inside. Movement of the positively charged sodium ion causes a change in the electrical potential of the cell near the Na+ gate. To compensate for the voltage change, the K+ gates open and Na+ gates close, allowing K+ to flow out of the cell. This results in an overcompensation of the voltage. The K+ gates close and <b>...</b>


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mitochondria dynamics (Ptk2-PY-Mitochondria)


Ptk2-PY-Mito: Ptk2 rat kangaroo kidney cells stably expressing PhiYellow-labelled mitochondria. Ideal tool for studies on mitochondrial behaviour and energy metabolism.


fluorescent stable cell line fluorescent Ptk2 fluorescent mitochondria MARINPHARM

Mitochondrial transport along microtubules


U20S cells were transduced with CellLight® MAP4-GFP and CellLight® Mito-RFP. Images were taken every 3 minutes for 30 minutes. A mitochondrion (red) can be seen transported along microtubules (green).


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